Potassium Nitrate is inorganic salt and active ingredient in toothpaste and protect the teeths from senstivity against cold and hot , senstivity can be reduce by acting on the intra-dental nerves and inhibit neural transmission .

Sodium fluoride is an inorganic compound which is the source of the fluoride ion which have many uses like it is used for dental care and in radiographic imaging.

Potassium is the over the counter de-sensitizing element that prevents the transmission of nerve endings to the teeth. potassium nitrate works by diffusion across the dentinal tubules, causing depolarization of the nerve cells.

Sodium fluoride kills bacteria that cause caries by interfering with their metabolic activities that result in the formation of lactic acid. It also inhibits the glycolytic and other enzymes involved in metabolism of bacteria